From Coordination Chemistry to Immune Modulation: Rational Design of Next‐Generation Mn 2+ ‐Based Immunomodulators
Mn 2+ has emerged as a potent immunostimulatory modulator capable of activating cyclic GMP–AMP synthase (cGAS)–stimulator of interferon genes (STING) and other innate immune signaling pathways. Consequently, Mn 2+ induces type I interferon responses, and promotes robust antitumor and antiviral immunity. Recent...