Author

Bing-Yan Li

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Sep 2026

Discovery of Emodin as a novel competitive KPC-2 inhibitor through virtual screening: Synergistic efficacy with Meropenem against Carbapenem-resistant Klebsiella pneumoniae infection.

Findings suggest that emodin acts as a promising candidate of KPC-2 inhibitor, which is capable of reinstating carbapenem efficacy against carbapenem-resistant Gram-negative pathogens in vitro and in vivo.

Yan Wang, Jia-Min Geng, Bing-Yan Li et al. · Bioorganic chemistry (Print) · 0 citations