Oct 2026
Tauroursodeoxycholic acid ameliorates DSS-induced ulcerative colitis via regulating TLR4/NLRP3/pyroptosis axis and Keap1/Nrf2 pathway and restoring gut barrier function.
Tauroursodeoxycholic acid (TUDCA) is a naturally occurring endogenous hydrophilic bile acid with therapeutic potential for ulcerative colitis (UC). However, the potential mechanism of its anti-UC effect remains unclear. Hence, this study investigated the therapeutic efficiency of TUDCA on dextran sulfate sodium (DSS)-i...
Jing-Yuan Liu, Xin-He Wang, Jia-Ying Wang et al.
· European Journal of Pharmaco... · 0 citations