Alleviation of hepatic ischemia-reperfusion injury by ginsenoside Rg5 and deoxyandrographolide through inhibition of SLC7A11/GPX4-mediated ferroptosis.
Shenfu Injection is a traditional Chinese medicine formulation widely used for cardiovascular and ischemic disorders. This study investigated the protective effects and underlying mechanisms of its bioactive constituents, ginsenoside Rg5 (Rg5) and deoxyandrographolide (DA), against hepatic ischemia-reperfusion injury (...