Author

Bingzhong Zhang

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Review Open access Oct 2026

Efficacy and Safety of Benmelstobart Plus Anlotinib in Advanced Endometrial Cancer: Results of a Multi‐Cohort, Phase II Study (ETER200)

ABSTRACT Patients with advanced endometrial cancer (EC) have a poor prognosis and limited therapeutic options after failure of prior systemic therapy. In this multi‐cohort Phase II study (ETER200), patients with metastatic or recurrent EC who had received at least one chemotherapy regimen were enrolled. Based on MSI/MM...

Shan-Hui Liang, Xiao-Jun Chen, Ke Wang et al. · MedComm · 0 citations

Open access Aug 2026

Integrative cfDNA profiling from low-pass whole-genome sequencing enables tissue-of-origin prediction in cancer

This stacked ensemble machine learning classifier that integrates 11 multidimensional cfDNA features spanning genomic, fragmentomic, methylation/repeat, and microbial signals provides a robust and non-invasive approach for accurate cancer type identification and has the potential to support clinical decision-making.

Yunjian Zhang, Liang Liu, H. Bao et al. · Molecular Biomedicine · 0 citations

Open access Aug 2026

Generalizable cancer detection from ultra-low-pass WGS via deep contextual modeling of cfDNA sequences

Fragmentia-AI™ WGS, a mutation-calling-independent framework that uses a transformer-based multiple-instance learning architecture with sequential fine-tuning across tumor fraction (TF) strata to extract latent cancer-associated signals from ULP-WGS data, enables robust cancer detection and clinically meaningful risk s...

Yang Xu, Song Wang, Guo-Feng Sun et al. · Molecular Biomedicine · 0 citations