Bingxue Song

Machine learning and single-cell RNA sequencing identify shared diagnostic genes and mechanistic links between antiphospholipid syndrome and carotid atherosclerosis

Background Antiphospholipid syndrome (APS) is an acquired autoimmune disorder characterized by recurrent vascular events in large, medium, or small vessels. These events contribute to cardiovascular disease primarily through thrombosis and atherosclerosis (AS). Carotid atherosclerosis (CAS) represents a particularly hi...