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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Bipul Nath

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2 papers indexed here

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Open access Aug 2026

DEVELOPMENT AND VALIDATION OF AN RP-HPLC BIOANALYTICAL METHOD FOR QUANTIFICATION OF RIZATRIPTAN BENZOATE IN RAT PLASMA AND BRAIN HOMOGENATE: APPLICATION TO PHARMACOKINETIC AND BRAIN-TARGETING STUDIES

Purpose This study was conducted to establish and validate a new, rapid, specific, sensitive and reproducible reverse-phase high performance liquid chromatographic (RP-HPLC) method for the determination of Rizatriptan Benzoate (RZT) in rat plasma and brain homogenate. The validated method was then used to assess the PK...

Priyanka Das, Bipul Nath, Payal Dasgupta et al. · 0 citations
Open access Jul 2026

Improving the biopharmaceutical performance of azole antifungals: a comparative study of solid dispersion and co-crystallization of ketoconazole and itraconazole

Background: Oral bioavailability of BCS class II azole antifungals, ketoconazole and itraconazole, is hampered by low aqueous solubility. Improving solubility and dissolution is necessary for greater therapeutic efficacy. This research compared two approaches: solid dispersion and pharmaceutical co-crystallization to i...

Payal Dasgupta, Bipul Nath, Apurba Talukdar et al. · 0 citations

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