Open access
Sep 2026
α-Synuclein Seeding Discriminates Between LRRK2 G2019S Variant Carriers with and Without Parkinson's Disease.
BACKGROUND Reliable biomarkers for Parkinson's disease (PD) pathology detection are essential for research. α-Synuclein (aSyn) seed amplification assay (SAA) is a validated biomarker for misfolded aSyn. OBJECTIVE The aim was to assess the association between aSyn SAA and LRRK2-related PD (LRRK2-PD) and its link to mi...
Theresa Lüth, C. Gabbert, T. Kleinz et al.
· Movement Disorders · 0 citations