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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Blerta Shtylla

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2 papers indexed here

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Review Open access 2026

Strategies for Successful Application of QSP Platform Models for Clinical Development and Regulatory Engagement

This review distills insights from a 2024 American Conference of Pharmacometrics session, highlighting real-world regulatory use cases including pediatric label extension, dose optimization in cell therapy, treatment duration for COVID-19 antivirals, and dosing strategies for T cell redirecting bispecific antibodies.

Wei-Rong Wang, Steven C. Chang, Mengdi Tao et al. · 0 citations
Review Open access Sep 2026

Quantitative Systems Pharmacology (QSP): Bridging Biology and Mechanism with Clinical Drug Development Decisions

This review outlines the historical development and conceptual foundations of QSP and summarizes representative clinical applications spanning early, mid, and late development, and considers emerging challenges and opportunities for QSP adoption.

Wei-Rong Wang, Alexander V. Ratushny, Steven C. Chang et al. · 0 citations

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