Author

Bo Dong

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Open access Oct 2026

High C1r expression is associated with cartilage damage in post-traumatic osteoarthritis.

. BACKGROUND The complement system undergoes extensive activation in osteoarthritis. Nevertheless, the specific function of C1r, a constituent of this system, in post-traumatic osteoarthritis (PTOA) remains unclear. PURPOSE To explore the clinical value and function of C1r in PTOA. METHODS Synovial fluid was obta...

Bo Dong, Kui Ma, Qi Dong et al. · Acta orthopaedica Belgica · 0 citations

Review Open access Oct 2026

Piezo1-centered mechanotransduction in knee osteoarthritis: multicompartment mechano-inflammatory networks and therapeutic opportunities

Knee osteoarthritis (KOA) is increasingly recognized as a whole-joint mechano-inflammatory disorder in which abnormal loading, tissue remodeling, and inflammatory sensitization reinforce one another. Piezo1 is a context-dependent mechanotransduction hub that links mechanical cues to Ca 2+ -dependent inflammatory,...

Jing Li, Bo Dong, Xue-Qin Zeng et al. · Arthritis Research & The... · 0 citations