Open access
Aug 2026
Deletion of Bmal1 in the Prelimbic Cortex Glutamatergic Neurons Triggers Schizophrenia-Like Behaviors in Mice.
Results reveal a previously unidentified role for Bmal1 deficiency in the PrL in driving SCZ-relevant negative symptoms and cognitive dysfunction, and provide experimental evidence supporting a putative role for dysregulated circadian clock gene expression in the pathogenesis of SCZ.
Yi-Qin Yao, Bo Guo, Zhi-Yi Xu et al.
· Schizophrenia bulletin · 0 citations