Integrative analysis reveals shared biomarkers and pathways in osteoporosis and rheumatoid arthritis using machine learning and single-cell sequencing
Background Osteoporosis (OP) and Rheumatoid Arthritis (RA) are prevalent chronic diseases characterized by bone loss and immune dysregulation. Evidence suggests that patients with RA are at increased risk of developing OP; however, the shared molecular mechanisms linking these conditions remain incompletely understood....