Review
Open access
Sep 2026
From Monovalent EV-A71 Vaccines to Multivalent Vaccines Against Hand, Foot and Mouth Disease in China: Development Progress, Evidence Gaps, and Translational Challenges
Hand, foot and mouth disease (HFMD) is caused by several enteroviruses, with enterovirus A71 (EV-A71) most strongly associated with severe disease and death. Licensed monovalent inactivated EV-A71 vaccines in China have a substantial evidence base for safety, immunogenicity, protective efficacy, and real-world effectiv...
Yi Zhang, Yu Gu, Zhi Li et al.
· Vaccines · 0 citations