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Author

Bo Huang

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Sep 2026

RUNX2 regulates cell proliferation, autophagy activity and apoptosis in LUAD cell via transcriptionally activating TMEM74.

Experimental results demonstrate that RUNX2 transcriptionally activates TMEM74, thereby promoting LUAD cell proliferation and autophagy and inhibiting cell apoptosis in vitro; TMEM74 knockdown suppresses tumor growth in vivo.

Ji Zhang, Yuan-Zhu Xia, Bo Huang et al. · 0 citations
Review Open access Jul 2026

Research progress on the regulation of mesothelioma driven by deubiquitinating enzyme BAP1.

Clinical and research priorities in elucidating the signaling pathways governed by BAP1, designing targeted therapeutic strategies for BAP1-mutant cancers, and implementing preventive interventions in BAP1 mutation carriers represent urgent clinical and research priorities.

Wan-Ting Xuan, Yao Dong, Sitong Ma et al. · 0 citations

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