Antibody- and enzyme-free point-of-care detection of procalcitonin via synergistic nanomachines-activated catalytic assembly (SNCA) assay for early sepsis monitoring.
Procalcitonin (PCT) is an important biomarker for the early assessment and dynamic monitoring of sepsis. However, its routine measurement largely relies on centralized laboratory testing and protein-based recognition or signal-amplification components. Here, we developed an antibody- and enzyme-free synergistic nanomac...