Identification of EGFR, MMP9, and AGTR1 as actionable therapeutic targets in acetyl tributyl citrate-driven breast cancer: integrated network toxicology and in vitro validation
Background Growing exposure to acetyl tributyl citrate (ATBC) drives breast cancer (BC) progression and poses significant challenges to clinical management. However, the precise molecular targets that mediate ATBC-induced tumor progression remain largely elusive. Identifying these cell surface and intracellular targets...