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Author

Bo Xiang

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Open access Aug 2026

LARS2 reprograms mitochondrial metabolism and epigenetically upregulates MHC-I to boost antitumor immunity in nasopharyngeal carcinoma

This study uncovers a novel mechanism by which the tumor suppressor LARS2 inhibits immune evasion in NPC through upregulation of MHC-I, and highlights a high-leucine diet as a promising strategy to sensitize tumors to immunotherapy.

Mei Yang, Yongzhen Mo, Dai-Xi Ren et al. · 0 citations

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