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Author

Bo Xiong

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Open access Jul 2026

Insufficiency of cohesin regulatory protein PDS5B triggers meiotic failure and aneuploidy in oocytes during advanced maternal aging.

It is found that the cohesin regulatory protein PDS5B, a dynamically maintained factor in oocytes, declines with age and plays a noncanonical role in the spindle pole formation independent of its cohesion function during oocyte meiotic maturation.

Yu Zhang, Jie Bai, Na Li et al. · 0 citations

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