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Review Open access Oct 2026

Public omics data reuse in gastric cancer: from discovery abundance to translational evidence

Public-omics data are now widely reused in gastric cancer bioinformatics. Resources such as The Cancer Genome Atlas stomach adenocarcinoma cohort (TCGA-STAD), the Gene Expression Omnibus (GEO), cBioPortal, proteogenomic cohorts, single-cell atlases, and spatial datasets make secondary analysis fast and inexpensive. The...

Shu-Qiong Su, Cong-Yi Huang, Bo Yang et al. · 0 citations
Oct 2026

LILRB3 as an ulcerative colitis-associated molecular biomarker: integrated transcriptomic, single-cell, and experimental validation.

OBJECTIVE Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by mucosal inflammation and immune dysregulation. Although macrophage-mediated inflammation is associated with UC progression, its molecular basis remains incompletely understood. This study integrated bioinformatic analyses and exp...

Bo Yang, Dong-Jie Sun, Zhu Liu et al. · 0 citations
Open access Aug 2026

An ICD gene set-derived immune contexture signature for colorectal cancer prognosis: integrated single-cell and bulk transcriptomic analysis with external validation.

Immunogenic cell death (ICD) links tumor cell demise with antitumor immunity, but the transcriptional features associated with ICD gene expression patterns and their prognostic significance in colorectal cancer (CRC) remain areas of active investigation. This study integrated single-cell and bulk transcriptomic data fr...

Shu-Qiong Su, Guo-Zhen Chen, Shi-Yao Yang et al. · 0 citations

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