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Open access Sep 2026

The capsid proteins of orthoflavivirus are interchangeable for West Nile virus assembly

ABSTRACT Orthoflavivirus virions consist of an envelope enclosing a nucleocapsid core. A critical step in orthoflavivirus assembly is the encapsidation of genomic RNA by the capsid protein to form the nucleocapsid. However, the molecular details of this process remain poorly understood, particularly whether capsid prot...

Jing Wang, Bao-Di Shang, Cheng-Lin Deng et al. · 0 citations
Open access Sep 2026

Triacylglycerol metabolism is a novel target to combat West Nile virus infection

The results unveil the importance of LDs and glycerolipid metabolism for WNV and highlight the potential of therapeutic interventions targeting this pathway to control viral replication and neuroinflammation.

F. Caridi, Patricia Mingo-Casas, Ana Esteban et al. · 0 citations
Open access Jul 2026

A single-dose chimeric Newcastle disease virus (NDV)/chikungunya virus (CHIKV) is an effective CHIKV vaccine candidate

A Newcastle disease virus (NDV) vector vaccine candidate expressing the complete envelope (E3–E1) protein of chikungunya virus (CHIKV) successfully develops a novel vaccine candidate that utilizes Newcastle disease virus as a vector to express CHIKV antigens.

Qiu-Yan Zhang, Yang Zhang, Zhe-Rui Zhang et al. · 0 citations

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