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Bohao Fang

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Open access Jul 2026

Harnessing the PpHog1 Regulatory Network to Engineer a UPR‐Adaptive Komagataella phaffii Chassis for High‐Copy Secretory Protein Production

An engineered UPR‐adaptive chassis (UPR‐Ad+) was constructed by over‐expressing these three key regulators and enhanced the production of high‐copy secretory proteins by 30%–46%.

Jiacheng Shi, Zhanqing Lv, Chaoyu Lu et al. · 0 citations