The bone marrow (BM) microenvironment is increasingly recognized as a dynamic immunometabolic niche that critically governs hematologic malignancies and BM-associated disorders, including acute myeloid leukemia (AML), multiple myeloma, myelodysplastic syndromes (MDS), metastatic infiltration, and aplastic anemia. At th...
Adrian Khu, A. P. Marpaung, Princella Halim et al.· Cell Biology International· 0 citations
Cancer remains one of the leading causes of mortality worldwide, accounting for approximately 20% of all deaths and posing a major threat to global health. Mechanistically, tumorigenesis is driven by complex molecular and cellular mechanisms that enable malignant cells to evade current therapeutic interventions, thereb...
Manish Kumar Singh, Hyeong Rok Yun, J. Ranbhise et al.· Cells· 0 citations
Atriplex halimus L. is a Mediterranean halophyte traditionally used in Moroccan ethnomedicine. The present study aimed to characterize the phytochemical profile of its aqueous (EA) and hydroethanolic (EHA) extracts and to provide a preliminary evaluation of their antibacterial and cytotoxic properties, supported by exp...
Mohammed Roubi, Ayoub Farihi, Mohammed Dalli et al.· Chemistry and Biodiversity· 0 citations
Introduction: The gut microbiome, host redox homeostasis, and immune regulation are mechanistically interdependent. However, their integrated role in driving resistance to immune checkpoint inhibitors remains incompletely defined.Objective: This review introduces the gut microbiome, immune, and antioxidant (GIA) axis a...
Muhammad Alaa Eldeen, Jinwon Choi, Hyo Jeong Kim et al.· Eurasian Journal of Medicine...· 0 citations
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