Author

Boyang Sun

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Open access Aug 2026

Comparative safety profiles of antibody-drug conjugates: a real-world analysis of monotherapy and combination regimens in solid tumors

Abstract The expanding clinical use of Antibody-Drug Conjugates (ADCs) necessitates a clearer understanding of their real-world toxicity profiles across diverse clinical settings. This retrospective pharmacovigilance study analyzed 19,697 adverse event (AE) reports for seven approved ADCs from the FDA Adverse Event Rep...

Linjie Fan, Yu-Ze Yin, W. Zhuang et al. · Drug Delivery · 0 citations

Open access Aug 2026

Genomic Profiling, Risk Stratification, and Post-Transformation Treatment Outcomes in Patients with Transformed Small-Cell Lung Cancer: A Multicenter Analysis.

BACKGROUND Transformed small-cell lung cancer (T-SCLC) is an increasingly recognized resistance mechanism in EGFR-mutant lung adenocarcinoma. This study aimed to identify early predictors of histologic transformation and evaluate post-transformation treatment outcomes. METHODS We retrospectively collected 163 T-SCLC...

Ruolin Gao, Zhenxiang Li, Jie-Ying Huang et al. · Lung Cancer · 0 citations