Single-cell sequencing reveals synovial fluid γδ T-cell expansion in equine experimental osteoarthritis.
Objective Define temporal cellular changes following joint injury using single-cell RNA sequencing in experimental equine posttraumatic osteoarthritis (PTOA). Methods PTOA was induced in 4 Quarter Horses (3 to 5 years) via carpal osteochondral fragmentation and high-speed treadmill exercise. Synovial fluid (SF) cells...