Review
Open access
Jul 2026
Applications and limitations of AI tools in enzyme design
A comprehensive introduction and overview of several current artificial intelligence (AI)‐driven methods available for enzyme design, with a focus on reaction‐to‐sequence design, structure prediction, substrate scope prediction, engineering of stable variants, design of enzymes with non‐canonical amino acids, and de novo design is offered.
Rosa Teijeiro-Juiz, Nina Egeler, Grzegorz Jamróg et al.
· Protein Science · 2 citations