Sodium depletion is associated with the response to glepaglutide in short bowel syndrome with chronic intestinal failure.
BACKGROUND & AIMS Glepaglutide, a long-acting glucagon-like peptide 2 (GLP-2) analogue, reduces the need for parenteral support (PS) and increases nutrient absorption including sodium, in patients with short-bowel syndrome (SBS). We retrospectively studied the association between sodium homeostasis based on urine sodiu...