Experimental and Theoretical Assessment of the Limited Viability of Alkyl Formates as Radical Precursors in Photocatalytic HAT/Decarboxylation Reactions
Hydrogen atom transfer (HAT) is widely employed in photocatalytic radical generation, with reactivity commonly rationalized through bond dissociation energies and activation barriers. In this context, alcohol-derived formates represent attractive traceless activating groups for radical-mediated alcohol diversification...