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Author

Bruno Mégarbane

2 papers indexed here

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Open access Aug 2026

Cocaine-Induced interindividual variability in female rats: From behavior to gene expression.

Cocaine use disorder is marked by strong interindividual variability, yet the molecular determinants underlying vulnerability in females remain poorly characterized. Here, we adapted a statistical model previously validated in males to classify female rats exposed to a cocaine-induced conditioned place preference parad...

Joséphine Gasparri, E. Curis, C. Eskenazi et al. · 0 citations
Open access Jul 2026

Individual differences in brain cocaine pharmacokinetics predict cocaine intake patterns in rats.

Pharmacokinetic factors play a critical role in cocaine use. Previous work mainly examined externally driven pharmacokinetic manipulations, showing that conditions producing rapid fluctuations in brain cocaine levels, such as intermittent versus continuous access, promote burst-like intake, increased motivation for coc...

D. Conlisk, Gabriela Goncalves Valente, J. Wiart et al. · 0 citations

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