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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

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Bryant J. Kane

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Open access Sep 2026

Impact of Renal Iron Overload on Sickle Cell Nephropathy in a Humanized Mouse Model.

Increased morbidity and mortality are associated with iron overload in sickle cell disease (SCD). Renal iron accumulation, a direct consequence of intravascular hemolysis, occurs in both patients and murine model of SCD, and correlates with albuminuria, an early marker of kidney injury. We aimed to investigate the role...

Mohammad O. Sako, Bryant J. Kane, Michael Booze et al. · 0 citations
Sep 2026

Endothelin Receptor Antagonism in Sickle Cell Disease: Is the Time Now?

Sickle cell disease (SCD) is a severe heritable hemoglobinopathy characterized by chronic hemolysis, episodic vaso-occlusion, and progressive multi-organ damage. Although hydroxyurea remains the most established disease-modifying therapy and that newer approaches such as L-glutamine, voxelotor, crizanlizumab, and gene...

Bryant J. Kane, V. Derebail, Malgorzata Kasztan · 0 citations

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