Bu-Yu Ke

The association between reduced hypothalamic subregion volume and aortic aneurysm risk: a Mendelian randomization and multi-omics study with clinical MRI validation

Background Aortic aneurysms represent significant cardiovascular pathologies with an incompletely understood pathogenesis. The hypothalamus, a critical structure in regulating autonomic functions, endocrine activity, and circadian rhythms, may play a role in this context. Methods We used Mendelian randomization (MR) to...