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Author

Butuo Li

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Open access Oct 2026

Golidocitinib ameliorates radio-immunotherapy-induced lung injury by alleviating oxidative stress and Pyroptosis.

BACKGROUND The combination of radiotherapy and immunotherapy (iRT) is effective against lung cancer but increases the risk of pulmonary toxicity. This iRT-induced lung injury (iRT-LI) may lead to treatment interruption and consequently worsen clinical outcomes. Golidocitinib, a selective JAK1 tyrosine-kinase inhibitor,...

Zhi-Ru Gao, Qian Zhao, Bu-Tuo Li et al. · 0 citations
Open access Jul 2026

Deep Learning-Driven Anticancer Drug Discovery: Emodepside as a Potential Therapeutic Candidate for Triple-Negative Breast Cancer

This study demonstrates the viability of the deep learning models to discover structurally novel anticancer agents that are distinct from conventional drugs, thereby expanding the therapeutic arsenal for TNBC patients.

Yiyue Xu, Taotao Dong, Butuo Li et al. · 0 citations

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