Preclinical development of ABL206, a novel bispecific antibody-drug conjugate targeting B7-H3 and ROR1
ABSTRACT Bispecific antibody-drug conjugates (BsADCs) represent a promising strategy to enhance tumor selectivity and overcome the limitations of monospecific ADCs. Here, we report the preclinical development of ABL206 (NEOK001), a novel BsADC targeting B7-H3 and ROR1, which are frequently co-expressed in various solid...