Review
Open access
Sep 2026
Targeting the IL-17A Cytokine Interface: Structural Insights and Small-Molecule Modulators
Interleukin-17A (IL-17A) is a proinflammatory cytokine that occupies a central position at the interface of host defense, tissue homeostasis, and chronic inflammation. While IL-17A plays essential roles in antimicrobial immunity and epithelial barrier integrity, dysregulated IL-17A signaling drives the pathogenesis o...
Gyeongmin Kim, Ansoo Lee, Sanghee Lee et al.
· Journal of Medicinal Chemist... · 0 citations