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Oct 2026

Functional involvement of HMGB1-related neuroinflammation in depression and its modulation by intermittent theta-burst stimulation(iTBS).

PURPOSE Intermittent theta-burst stimulation (iTBS) is widely used for its rapid antidepressant efficacy in clinical practice. However, its underlying neuroimmune mechanisms and objective biomarkers of treatment response remain largely unexplored. High mobility group box 1 (HMGB1), a critical driver of neuroimmune inte...

Ya-Xing Zhang, Shi-Yu Xin, Kai-Ming Zhang et al. · 0 citations
Open access Sep 2026

214. Magnetic seizure therapy for major depressive disorder: clinical efficacy, safety, and prefrontal activation measured by functional near-infrared spectroscopy

Abstract Background Magnetic seizure therapy (MST) is an emerging convulsive neuromodulation technique that may achieve antidepressant efficacy comparable to electroconvulsive therapy (ECT) while minimizing cognitive adverse effects. However, neurophysiological mechanisms underlying its therapeutic action remain incomp...

R. Wang, L. Jiao, C. An · 0 citations

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