Author

C. Angelini

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Open access Aug 2026

Regulatory mutants of the Tbx1 gene alter transcription programs of lineage determination and patterning in early mesoderm

The Tbx1 gene is haploinsufficient in mice and in humans, where it causes a DiGeorge syndrome phenotype characterized by developmental deficits of the pharyngeal apparatus. TBX1 plays a critical role in the differentiation and regionalization of the cardiopharyngeal mesoderm lineage and its derivatives. Nevertheless, i...

S. Allegretti, O. Lanzetta, M. Bilio et al. · bioRxiv · 0 citations

Open access Jul 2026

scGraphVerse: a modular workflow for single-cell gene network inference

Abstract Motivation Inferring gene networks from single-cell RNA sequencing data is challenging due to high sparsity, dimensionality, and technical noise. Current pipelines lack the multi-dataset integration and comprehensive post-processing analysis. Results scGraphVerse is an R package that integrates multiple algori...

Francesco Cecere, D. De Canditiis, Annamaria Carissimo et al. · Bioinformatics Advances · 0 citations

Preprint Aug 2026

Uncovering Cellular Resolution in scRNAseq via Unbiased Cell and Gene Network Analysis

The results indicate that GmGM provides a unified, reproducible framework for joint cell clustering and gene-network inference, capable of revealing cellular structure beyond that captured by conventional pipelines.

O. Lanzetta, L. Cutillo, Bailey Andrew et al. · 0 citations