Author

C. Assenmacher

2 papers indexed here

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Open access Sep 2026

Proton FLASH radiotherapy enhances control of triple-negative breast cancer through STING–IRF3 and CD8+ T-cell immunity

FLASH radiotherapy delivers radiation at ultra-high dose rates and has been demonstrated to spare normal tissue compared to standard radiotherapy, but it is not known if dose rate also modifies tumor response. Here we compare a single 13.5 Gy fraction of proton irradiation delivered at FLASH (F-PRT) or Standard (S-PRT)...

P. Loap, Ioannis Paraskevaidis, C. Cheptea et al. · bioRxiv · 0 citations

Oct 2026

A fluorescent choline kinase alpha inhibitor for intraoperative molecular imaging during resection of canine NSCLC tumors.

Choline kinase α (ChoKα) is a biomarker of lung cancer, is overexpressed in 60% of human pulmonary malignancies, and is associated with an aggressive phenotype and poor clinical outcome. Patients with lung cancer who undergo surgery have a recurrence rate of 30 to 50%, indicating a potential need for better tumor detec...

Sofya A. Osharovich, David E. Holt, Michael C. Hart et al. · Science Translational Medici... · 0 citations