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Author

C. Ballard

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Meta-analysis Open access Sep 2026

Interrogating DNA methylation associated with Lewy body pathology in a cross brain-region and multi-cohort study

Here, we conduct a large meta-analysis of DNA methylation across multiple cortical brain regions, in relation to increasing burden of Lewy body pathology. Utilizing a dataset of 1205 samples (832 unique donors), we identify 24 false discovery rate significant differentially methylated loci associated with Lewy body pat...

Joshua Harvey, J. Imm, Morteza Kouhsar et al. · 0 citations
Open access Sep 2026

Cognitive reserve and everyday functioning in cognitively unimpaired older adults: evidence from the CAN-PROTECT study

Abstract Background Cognitive reserve (CR) is thought to buffer against the clinical manifestation of dementia, preserving cognitive function despite accumulating pathology. However, less is known about how CR relates to the capacity to independently perform activities of daily living (ADL), particularly among cognitiv...

M. Ghahremani, Dylan X. Guan, C. Ballard et al. · 0 citations

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