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Author

C. F. Bennett

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Sep 2026

Automated Multimodal Correlative Registration for Organelle-Specific Elemental and Isotopic Imaging.

Mapping the subcellular partitioning of therapeutics is important for understanding their trafficking, mechanisms of action, and off-target effects. NanoSIMS provides chemical images of labeled therapeutics, but assigning these signals to cellular structures requires correlation with electron microscopy (EM). This corr...

Chi-Xiang Lu, Kai-Qiang Zhao, D. Cui et al. · 0 citations
Open access Jul 2026

Individualized antisense oligonucleotides for SCN2A-related developmental epileptic encephalopathy

In two patients with SCN2A epileptic encephalopathy, treatment with personalized allele-selective antisense oligonucleotides led to a decrease in seizure frequency with a positive safety profile, and a pathway from n = 1 to n of more patients with SCN2A-RD and other monogenic disorders is provided.

Olivia Kim-Mcmanus, L. Mignon, J. Douville et al. · 2 citations

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