Sonic Hedgehog Is An Important Regulator Of Intervertebral Disc Homeostasis And Rejuvenation
Intervertebral disc degeneration and associated neurological symptoms constitute a global health burden, yet no cure is currently available 1,2. Each disc consists of a central nucleus pulposus, surrounded by annulus fibrosus, and end plates connecting it to the growth plates of adjacent vertebral bodies. The notochord...