Open access
Aug 2026
IL-15 boosts mesothelin- and CD70-CAR NK cell potency in PDAC without added benefit from dual targeting
Findings highlight the limitations of dual-targeting approaches and underscore the need for advanced engineering strategies to improve CAR NK cells beyond antigen targeting and cytokine support in the PDAC microenvironment.
Laura Gehrcken, J. Ott, Astrid Van Den Eynde et al.
· Molecular therapy. Oncology · 1 citation