Author

C. Decarli

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Open access Sep 2026

Oxygen extraction fraction mapping between normal cognition and mild cognitive impairment in older adults using quantitative BOLD

Abstract Oxygen extraction fraction (OEF) represents the proportion of oxygen utilized by the brain from the blood and is a sensitive biomarker in understanding the vascular interplay between oxygen supply and demand. Alterations in OEF are increasingly recognized in normal aging and the pathophysiology of many neurolo...

Linh N. N. Le, Gregory J. Wheeler, Nicholas P. Blockley et al. · Imaging neuroscience · 0 citations

Aug 2026

Mid-life candidate vascular plasma biomarkers are associated with MRI markers of vascular brain injury and amyloid- and tau-PET in cognitively healthy adults

Background Identifying candidate biomarkers for preclinical dementia could improve our understanding of underlying biological pathways leading to vascular brain injury (VBI) and neurodegeneration. Objective To identify plasma protein markers of MRI markers of VBI and amyloid- and tau-PET burden in cognitively healthy a...

Martin D. Mulligan, Rui-Qi Wang, Qiong Yang et al. · Journal of Alzheimer's Disea... · 0 citations

Open access Jul 2026

Using Polygenic Risk Scores to Evaluate Definitions of Self-Reported Sleep Phenotypes Across Cohorts.

Which sleep PRS performed well across diverse populations and which sleep definitions better captured genetic underpinnings was highlighted by evaluating several types of sleep PRSs and sleep phenotypes.

A. Wyss, Michael Brown, Xiang Li et al. · Sleep · 0 citations