RP-HPLC METHOD FOR DISSOLUTION TESTING OF CAPECITABINE TABLETS
The United States Pharmacopeia (USP) monograph for capecitabine tablets uses a UV spectrophotometric method for dissolution testing, although UV detection lacks selectivity for capecitabine over co-absorbing excipients or degradation products. In the present study, an isocratic RP-HPLC technique was developed and valid...