Open access
Jul 2026
An endogenous retrovirus insertion disrupting bovine ALKBH8 causes a failure-to-thrive syndrome with immunodeficiency associated with juvenile mortality in Brown Swiss cattle
This study demonstrates that exploring population-scale genomic data and mining thousands of life-history records, followed by veterinary follow-up evaluations and molecular genetic analyses, provides an effective strategy for identifying cryptic recessive disorders that shorten the lifespan of cattle.
S. Glatthard, N. Kadri, F. Seefried et al.
· bioRxiv · 0 citations