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Author

C. Engelman

3 papers indexed here

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Sep 2026

Multi-omics integration of transcriptomics and metabolomics with machine learning uncovers novel risk factors for Alzheimer's disease.

BackgroundAlzheimer's disease (AD) is a neurodegenerative disorder characterized by cognitive decline, memory impairment, and functional deterioration. Its complex pathogenesis involves amyloid plaques, tau tangles, neuroinflammation, synaptic dysfunction, and interacting genetic, environmental, and lifestyle factors....

Jerome J. Choi, C. Engelman, Tianyuan Lu · 0 citations
Open access Sep 2026

Plasma P-tau217, APOE Genotype, and the Timing of Cognitive Impairment in individuals Across Diverse Racial and Ethnic Groups: A Pooled Analysis of Prospective Cohort Studies

Findings support the use of biomarker-informed approaches to guide monitoring and therapeutic intervention in appropriately selected at-risk individuals before the onset of clinical symptoms and support the use of biomarker-informed approaches to guide monitoring and therapeutic intervention.

Yue-Xuan Xu, T. I. Gunasekaran, Yian Gu et al. · 0 citations

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