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C. Erickson

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Open access Sep 2026

Heterogeneity of brain dynamics in genetic and psychiatric conditions

Whether the heterogeneity of psychiatric conditions converges on shared neurophysiological alterations or translates into distinct signatures remains unclear. We assembled high-density electroencephalogram (hd-EEG) resting-state recordings from 4,812 individuals aged 5 months to 66 years across 11 psychiatric condition...

Adrien E. E. Dubois, Sarah Lippé, Charles-Olivier Martin et al. · 0 citations
Open access Sep 2026

Atlas-Based Electrical Source Imaging for Mouse EEG: Application to an Fmr1 Knockout Model.

Electrical source imaging (ESI) reconstructs where in the brain a scalp EEG signal arises. It is routine in humans but unestablished in the mouse, whose brain is some 3,000 times smaller where it is not obvious that a sparse array can separate one region from another. We built an atlas-based ESI pipeline for 30-channel...

Alex D. Edmondson, Andrew D. Gaulden, Richard K. Lacher et al. · 0 citations
Open access Jul 2026

FMR1 gene therapy restores translationally relevant phenotypes in a mouse model for fragile X syndrome.

It is shown that FMR1 gene therapy using delivery routes and vehicles approved for clinical use improves core phenotypes in a mouse model for FXS, and suggests that a dual route may be needed to achieve full brain coverage.

Richard K Lacher, Kari Henson, Lindsay N Wathen et al. · 0 citations

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