Natural Bone Regeneration-Inspired Poly(Lipoic Acid)-Based Organic-Inorganic Bone Adhesive for Osteoporotic Bone Defect Repair.
Osteoporosis, featured by imbalanced bone remodeling, faces clinical challenges including microenvironment dysregulation, insufficient mineralization, and poor material fixation. Inspired by natural bone regeneration-where ossification centers and surrounding soft tissues orchestrate mineralization and tissue integrati...