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C. Feng

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Open access Sep 2026

Atherosclerotic plaque fibroblasts derive from adventitial and medial Pdgfra-lineage-positive cells and predominantly maintain fibroblast identity.

AIMS Fibroblasts are mesenchymal cells in the healthy vascular adventitia. In atherosclerosis, single-cell sequencing datasets suggest fibroblasts are abundant in plaques. However, their identity, origin, and fate during plaque progression remain unclear, which we aim to unravel here. APPROACH AND RESULTS To robustly...

Guan-Liang Li, S. Asselberghs, Bai-Xue Yu et al. · 0 citations
Review Open access Aug 2026

Deep Learning for Deciphering the Plant Cis-Regulatory Code

This review compares convolutional, Transformer-based and graph architectures used to represent local sequence features, chromatin state and three-dimensional genome organisation to their applications to transcription-factor binding, chromatin accessibility, gene expression, non-coding variant prioritisation and regula...

Zhi-Meng Zhao, Si-Xuan Huang, Shi-Long Zhang et al. · 0 citations

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