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Author

C. Fenoglio

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Open access Sep 2026

Exploring the interplay between frailty, Alzheimer's disease biomarkers, and cognitive functioning in patients with mild cognitive impairment: A cross-sectional study

Background Frailty is characterized by declining homeostatic reserves and increased vulnerability to stressors, and has been associated with cognitive decline and dementia. Objective To examine the relationship between frailty, Alzheimer's disease (AD) biomarkers, and cognitive performance in individuals with mild cogn...

Manuela Pintus, M. Valletta, L. Sacchi et al. · 0 citations
#diffusion models Open access Sep 2026

Assessing glymphatic role in the association between choroid plexus enlargement and white matter lesions load: The uncertain path through diffusion tensor imaging along the perivascular space (DTI-ALPS).

CP enlargement is associated with reduced DTI-ALPS and greater WML burden, but the contribution of glymphatic impairment remains uncertain, and alternative mechanisms may contribute to these findings.

L. Sacchi, Valentina Veronesi, Giorgio Bocca et al. · 0 citations
Open access Sep 2026

Microglia-derived extracellular vesicles uncover early alterations of inflammatory signaling in Alzheimer's disease.

Findings support the presence of a compartment-specific reorganization of inflammatory signalling during AD progression and highlight the potential of MDEVs as accessible peripheral biomarkers of neuroinflammatory processes in AD.

Chiara Bianchessi, M. Serpente, E. Ferri et al. · 0 citations
Open access Aug 2026

Educational attainment and sex modulate clinical outcomes in genetic frontotemporal dementia

Sex and educational attainment significantly affect the development and maintenance of cognitive reserve in individuals with genetic FTD, and underscore the importance of identifying disease-modifying interventions since the presymptomatic stages of the disease.

E. Premi, Damiano Archetti, A. Redolfi et al. · 0 citations

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