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Open access Oct 2026

Identification of PAK Gene Fusions in an Ovarian and a Testicular Serous Carcinoma.

This report describes two unique gonadal serous carcinomas, one low-grade serous carcinoma (LGSC) of the ovary and one serous carcinoma of the scrotum each harboring novel PAK gene fusions. The first patient with ovarian LGSC was identified to have a PTPRM::PAK1 fusion, identifying PTPRM as a novel fusion partner for P...

N. Khorsandi, Jeffry P. Simko, W. P. Devine et al. · 0 citations
Open access Oct 2026

Pyelonephritis is associated with persistent alterations in immune-stromal and vascular programs in the human placenta

The villous immune-stromal-vascular microenvironment is identified as a persistent site of placental remodeling following maternal infection and suggest that clinical recovery from maternal illness may not coincide with normalization of placental biology.

C. Blauvelt, N. Ozarslan, S.-M. Tsoi et al. · 0 citations

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