Author

C. Gianni

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Open access Oct 2026

Oral anticoagulation regimen after left atrial appendage occlusion in elderly atrial fibrillation patients with versus without cardiovascular comorbidities

Antithrombotic therapy is used after left atrial appendage occlusion (LAAO) to prevent device-related thrombosis (DRT) that could lead to stroke or transient ischemic attack (TIA). Ageing in atrial fibrillation (AF) as well as many age-associated comorbidities are known risk factor for stroke. Moreover, bleeding...

S. Mohanty, V. L. La Fazia, C. Gianni et al. · European Heart Journal · 0 citations

Open access Oct 2026

Long-term efficacy of pulsed-field ablation devices in real-world atrial fibrillation patients: a direct comparison between the Farapulse and the Affera ablation systems

Pulsed-field ablation (PFA) with its characteristic high tissue-selectivity, has recently emerged as a promising alternative to the conventional radiofrequency ablation for the management of atrial fibrillation (AF). This study evaluated the safety and efficacy of two systems using either a pentaspline or a latti...

S. Mohanty, V. L. La Fazia, C. Gianni et al. · European Heart Journal · 0 citations

Review Sep 2026

Left Atrial Appendage Closure: Past, Present, and Future

Left atrial appendage closure (LAAC) has emerged as an important alternative strategy for stroke prevention in patients with non-valvular atrial fibrillation (NVAF), particularly when long-term oral anticoagulation (OAC) is contraindicated or poorly tolerated. Initially developed as a surgical technique based on ligati...

E. Zito, Pamela Horton Embrey, V. L. La Fazia et al. · Journal of Innovations in Ca... · 0 citations